某一天小鲜肉来到我家门前

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　　On her final combat mission across the rugged mountains of Afghanistan, Royal Air Force fighter pilot Lt. Kate Sinclair’s jet is shot down over one of the most dangerous rebel strongholds. When insurgents come after her at the crash site, she finds refuge in a long since abandoned underground bunker. After tracking Sinclair into the depths of the bunker, the insurgents accidentally awaken a man-made deadly biological weapon known as the Ravagers - half human, half alien and hungry for human flesh. Terrified, she watches the creatures rip apart the men pursuing her. Sinclair barely escapes and is picked up by a US army patrol sent to find her. Major Roy Finch, commander of the local US army outpost ‘Fort Apache’, and his ragtag squad of brave soldiers have a difficult time believing mutant monsters have been kept hidden in these mountains. Unaware that she has been tracked to their base, dozens of the vicious creatures are already swarming towards them.

　　故事发生在2029年，彼时，X战警早已经解散，作为为数不多的仅存的变种人，金刚狼罗根（休·杰克曼 Hugh Jackman 饰）和卡利班（斯戴芬·莫昌特 Stephen Merchant 饰）照顾着年迈的X教授（帕特里克·斯图尔特 Patrick Stewart 饰），由于衰老，X教授已经丧失了对于自己超能力的控制，如果不依赖药物，他的超能力就会失控，在全球范围内制造无法挽回的灾难。不仅如此，金刚狼的自愈能力亦随着时间的流逝逐渐减弱，体能和力量都早已经大不如从前。　　某日，一位陌生女子找到了金刚狼，将一个名为劳拉（达芙妮·基恩 Dafne Keen 饰）的女孩托付给他，嘱咐他将劳拉送往位于加拿大边境的“伊甸园”。让罗根没有想到的是，劳拉竟然是被植入了自己的基因而培养出的人造变种人，而在传说中的伊甸园里，有着一群和劳拉境遇相似的孩子。邪恶的唐纳德（波伊德·霍布鲁克 Boyd Holbrook 饰）紧紧的追踪着罗根一行人的踪迹，他的目标只有一个，就是将那群人造变种人彻底毁灭。